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8119695 |
Compounds and methods for treating breast cancer and other diseases
Disclosed are novel compositions and novel methods for the creation of both the novel compounds and known compounds. Also disclosed are methods for use of the novel compounds for treating a variety...
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8119638 |
Compositions and uses of ET743 for treating cancer
Et 743 is used in the preparation of a medicament for the treatment of the human body for cancer.
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8119596 |
Composition with anti-inflammatory, protein synthesizing, enzyme deficiency activating genetic therapy and anti-cancer activity and methods of use
A composition for treating damaged tissue and promoting healthy tissue growth, healing and tissue regeneration, wherein said composition comprises an extracellular matrix compound, a surface-active...
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8119418 |
Monitoring treatment of colorectal cancer patients with drugs targeting EGFR pathway using mass spectrometry of patient samples
Methods using mass spectral data analysis and a classification algorithm provide an ability to determine whether a non-small-cell lung cancer patient, head and neck squamous cell carcinoma or...
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8119417 |
Monitoring treatment of head and neck cancer patients with drugs EGFR pathway using mass spectrometry of patient samples
Methods using mass spectral data analysis and a classification algorithm provide an ability to determine whether a non-small-cell lung cancer patient, head and neck squamous cell carcinoma or...
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8119355 |
Biomarkers for cancer sensitivity and uses thereof
Disclosed herein are biomarkers and uses thereof for evaluating anti-cancer efficacy and sensitivity.
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8119138 |
Anti-estrogen and immune modulator combinations for treating breast cancer
Compositions for treating cancers of mucosal tissues including breast, prostate, ovary, colon are disclosed which include various combinations of new or conventional anti-estrogen compounds,...
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8119116 |
Therapeutics for cancer using 3-bromopyruvate and other selective inhibitors of ATP production
The present invention relates to methods of treating a cancerous tumor using selective inhibitors of ATP production. The present invention also relates to pharmaceutical preparations comprising...
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8116546 |
Lung cancer diagnosis using magnetic resonance imaging data obtained at three time points
A malignancy classification method and medium for diagnosing a region of lung tissue based on MRI data are disclosed. The classifying includes: setting time points T1 and T2 measured from injection...
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8114914 |
Topical vasoconstrictor preparations and methods for protecting cells during cancer chemotherapy and radiotherapy
Vasoconstrictors are administered topically to provide protection against the adverse effects, e.g., alopecia, mucositis or dermatitis, induced by chemotherapy or radiotherapy. Appropriate dosages...
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8114882 |
(1H-indol-7-yl)-(pyrimidin-2-ylamino)methanone derivatives and related compounds as IGF-R1 inhibitors for the treatment of cancer
The invention relates to compounds of the formula (I), in which Ar denotes a mono- or bicyclic aromatic homo- or heterocycle having 1 to 4 N, O and/or S atoms and 5 to 10 skeleton atoms, which may...
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8114865 |
Indazole derivatives as kinase inhibitors for the treatment of cancer
Substituted indazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions...
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8114674 |
Method for determining whether or not a mammal is affected with a lung cancer
The present invention relates to a method for determining whether or not a mammal is affected with a lung cancer. The method for determining whether or not a mammal is affected with a lung cancer...
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8114593 |
Cancer biomarker genes and gene products and methods for using the same
Using gene expression analysis, specific biomarker genes and gene products have been identified which are activated in transformed cells, but suppressed in nontransformed cells; or suppressed in...
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8114587 |
Methods for the detection of colorectal cancer
This invention relates to non-radioactive markers that facilitate the detection and analysis of nascent proteins translated within cellular or cell-free translation systems. Nascent proteins...
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8114414 |
Compositions and methods for treatment of cervical cancer
The present invention provides methods of treating, protecting against, and inducing an immune response against cervical cancer, comprising the step of administering to a subject a recombinant...
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8114405 |
Cancer vaccine based on brother of regulator of imprinted sites molecule (BORIS)
Polynucleotides encoding a nonfunctional mutant form of the Brother of Regulator of Imprinted Sites (BORIS) molecule, nonfunctional mutated BORIS protein, polypeptide or peptide and modified...
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8110654 |
T cell epitope peptides of ovarian cancer anti-idiotypic antibody 6B11 and use thereof
The present invention provides two T-cell epitode peptides of anti-idiotype antibody 6B11 of ovarian cancer, the sequences of which are shown in SEQ ID NO:3 or 6. The present invention also...
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8110550 |
HDAC inhibitors and hormone targeted drugs for the treatment of cancer
The present invention relates to the methods of treating endocrine-regulated cancers, including hormone resistant cancers, for example. More specifically, the present invention relates to a method...
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8110544 |
RasGAP derived peptide for selectively killing cancer cells
The present invention relates to a peptide consisting in the N2 sequence of the RasGAP protein, a fragment thereof, or a variant thereof which enhances the ability of a drug to selectively kill...
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8110375 |
High throughput assay for cancer cell growth inhibition
A high-throughput, anchorage-independent assay is described, which screens compounds for inhibition of cancer cell growth. The assay utilizes a three-dimensional matrix or semi-solid media...
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8110370 |
IBC-1 (Invasive Breast Cancer-1), a putative oncogene amplified in breast cancer
This invention encompasses antibodies specific for IBC-1 (Invasive Breast Cancer-1), methods for diagnosis and prognosis of metastatic breast cancer and degenerative neural conditions, methods of...
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8110363 |
Expression profiles to predict relapse of prostate cancer
The present invention provides a method for preparing a reference model for cancer relapse prediction that provides higher resolution grading than Gleason score alone. The method encompasses...
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8110362 |
Method for determining a tongue cancer
An object is to provide: a method for determining a tongue cancer in which the malignancy of tongue cancer can be objectively and accurately determined; a method for analyzing a tongue cancer...
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8110361 |
DNA methylation markers associated with the CpG island methylator phenotype (CIMP) in human colorectal cancer
Particular aspects confirm the existence of a CpG island methylator phenotype (CIMP) in colorectal cancer, and provide novel validated DNA methylation markers associated with CIMP. Additional...
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8110358 |
Method of profiling gene expression in a subject having prostate cancer
The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and...
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8110352 |
Method of diagnosing and treating cancer using B-catenin splice variants
The invention relates to method of diagnosing and treating cancer, in particular β-catenin related cancers. The invention further relates to methods of identifying CTNNB1 related cancer CTNNB1 ...
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8110347 |
Diagnostic method for detecting cancer by measuring amount of cytokine like IL-6
The present invention relates to a diagnostic method for predicting the possible recurrence of tumors in cancer patients. The method comprises culturing blood cells from a patient suffering from...
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8106024 |
Method of treating cancer with an RPN2 gene expression inhibitor
The present invention uses an RPN2 gene expression inhibitor as a cancer cell growth inhibitor, which further includes a drug showing an anti-cancer action if desired, and is administered in...
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8106002 |
Anti-cancer agent comprising protein C inhibitor
The present invention provides anti-cancer agents comprising protein C inhibitor (PCI) or derivatives thereof as an active ingredient. The anti-cancer agents of the present invention have...
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8105777 |
Methods for diagnosis and/or prognosis of colon cancer
The present invention relates to genetic markers whose expression is correlated with colon cancer. In one aspect, the invention provides sets of markers whose expression can be used for classifying...
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8105773 |
Oligonucleotides for cancer diagnosis
The present invention provides sets of oligonucleotides corresponding to genes encoding proteins involved in protein synthesis and/or stability or genes encoding proteins involved in the regulation...
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8105769 |
Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments
The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at...
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8105615 |
Lactoferrin as an adjuvant in cancer vaccines
The present invention relates to methods of treating cancer by administering a composition of lactoferrin (LF) in combination with cancer vaccines.
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8101773 |
Hydroxy methyl phenyl pyrazolyl urea compounds useful in the treatment of cancer
The compound 4-{4-[({3-tert-Butyl-1-[3-(hydroxymethyl)phenyl]-1H-pyrazol-
5-yl}carbamoyl)amino]-3-fluorophenoxy}-N-methylpyridine-2-ca
rboxamide and alternative forms thereof (e.g., salts,...
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8101713 |
Prostate cancer diagnosis and treatment
The present invention relates to novel antibodies and their use for detecting, imaging, staging, treating and monitoring of prostate cancer, and/or metastasis thereof. The present invention also...
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8101662 |
Treatment of cancer with specific RXR agonists
A method of treating cancer is disclosed comprising administering to a patient in need of such treatment a RXR agonist at a level below the RAR activating threshold and at or above the RXR...
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8101660 |
Use of 2,5-dihydroxybenzene compounds and derivatives for the treatment of skin cancer
The present invention relates to the use of a 2,5-dihydroxybenzene derivative of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or...
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8101628 |
Imidazolidinonyl aminopyrimidine compounds for the treatment of cancer
The present invention provides novel imidazolidinonyl aminopyrimidine compounds believed to have clinical use for treatment of cancer through inhibiting Plk1. wherein: R1 hydrogen, hydroxy, halo,...
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8101372 |
Diagnosis and therapy of cancer using SGP28-related molecules
The present invention relates to methods and compositions for the diagnosis and therapy of prostate cancer which utilize isolated polynucleotides corresponding to the human SGP28 gene, proteins...
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8101371 |
Methods for the diagnosis of genitourinary cancer
Methods for the diagnosis of genitourinary (GU) cancer are provided. In particular, urine has been found to contain significant levels of thromboxane receptor β (TPβ) methods for diagnosing GU c...
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8101359 |
Method for determining risk of relapse of breast cancer following tamoxifen adjuvant therapy
The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for...
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8101352 |
Detection of ESR1 amplification in breast cancer
The present invention relates to an in-vitro method of identifying a tumor resulting from a proliferative breast disease as responsive to anti-estrogen treatment. Further, the invention relates to...
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8101342 |
DNA vaccine for treating or preventing cervical cancer comprising a gene encoding HPV protein
Disclosed herein is a DNA vaccine for treating cervical cancer including an E5 gene of human papillomavirus (HPV). Also, disclosed is a combination DNA vaccine for preventing and treating cervical...
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8101195 |
Artificial lymph node for treating cancer
Provided is an artificial lymph node that is persistently effective in cancer treatment in vivo. A method of producing an artificial lymph node capable of inducing cancer antigen-specific immune...
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8101173 |
Method for treating urinary bladder cancer
The present invention discloses an immunotherapeutic method for treating a patient suffering from urinary bladder cancer by administering expanded tumour-reactive CD4+ helper and/or CD8+...
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8101159 |
In vivo methods of identifying compounds which target suppressed cancer cells
In vitro and in vivo methods for identifying compounds capable of targeting suppressed cancer cells such as micrometastatic cells. The in vitro method includes the steps of comparing the response...
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8100839 |
Acoustic monitoring of a breast and sound databases for improved detection of breast cancer
Provided are methods and devices that pertain to the acquisition of data related to breast vascularity associated with breast cancer, use of data, or both, that are associated with the generation...
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8097648 |
Methods and compositions for use in treating cancer
The invention provides methods and compositions for use in treating diseases associated with excessive cellular proliferation, such as cancer.
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8097595 |
Modulation of telomere length in telomerase positive cells and cancer therapy
Induction of telomere shortening, G2 arrest and apoptosis in telomerase positive cancer cells using acyclic nucleoside analogs has been disclosed. In addition, methods for impairment or prevention...
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